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In none of the subgroups did the magnesium sulfate group show a better outcome at 6 months. Secondary outcome analyses modified Rankin Scale, Barthel Index, Short Form 36, and clinical vasospasm also showed no significant differences between the 2 groups. Secondary outcome analyses modified Rankin Scale, Barthel Index, Short Form 36, and clinical vasospasm also showed no significant differences between the 2 groups. In none of the subgroups did the magnesium sulfate group show a better outcome at 6 months.

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This Phase III study aimed to compare intravenous magnesium sulfate infusion with saline placebo among such patients. We recruited patients with aneurysmal subarachnoid hemorrhage within 48 hours of onset from 10 participating centers. Epub Apr 8.

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Curr Neurol Neurosci Rep. The results do not support a clinical benefit of intravenous magnesium sulfate infusion over placebo infusion in patients with acute aneurysmal subarachnoid hemorrhage.

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Of the patients recruited, were randomized to receive treatment with intravenous magnesium sulfate and to receive saline placebo. The results do not support a clinical benefit of intravenous magnesium sulfate infusion over placebo infusion in patients with acute aneurysmal subarachnoid hemorrhage.

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Predefined subgroups included age, admission World Federation of Neurological Surgeons grade, pre-existing hypertension, intracerebral hematoma, intraventricular hemorrhage, location of aneurysm, size of aneurysm, and mode of aneurysm treatment. Curr Neurol Neurosci Rep. Epub Apr 8. We recruited patients with aneurysmal subarachnoid hemorrhage within 48 hours of onset from 10 participating centers.

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The patients were randomly assigned to magnesium sulfate infusion titrated to a serum magnesium concentration twice the baseline concentration or saline placebo for 10 to 14 days. Curr Neurol Neurosci Rep. Epub Apr 8. The results do not support a clinical benefit of intravenous magnesium sulfate infusion over placebo infusion in patients with acute aneurysmal subarachnoid hemorrhage.

Apr 8, - Intravenous magnesium sulphate for aneurysmal subarachnoid hemorrhage (IMASH): a randomized, double-blinded, placebo-controlled. Apr 8, - Intravenous magnesium sulphate for aneurysmal subarachnoid hemorrhage (IMASH): a randomized, double-blinded, placebo-controlled. Where: The Grove Hotel and Boise Centre, Boise, Idaho. About: Colorado, Idaho, Utah and Wyoming have once again teamed up to bring you a Convention full.

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Of the patients recruited, were randomized to receive treatment with intravenous magnesium sulfate and to receive saline placebo. We recruited patients with aneurysmal subarachnoid hemorrhage within 48 hours of onset from 10 participating centers. Secondary outcome analyses modified Rankin Scale, Barthel Index, Short Form 36, and clinical vasospasm also showed no significant differences between the 2 groups.

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The study is registered at www. Epub Apr 8.

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5 Commentsto Imash

  1. Faejinn says:

    Curr Neurol Neurosci Rep. Epub Apr 8.

  2. Akilrajas says:

    Epub Apr 8. Secondary outcome analyses modified Rankin Scale, Barthel Index, Short Form 36, and clinical vasospasm also showed no significant differences between the 2 groups.

  3. Shaktizuru says:

    The patients were randomly assigned to magnesium sulfate infusion titrated to a serum magnesium concentration twice the baseline concentration or saline placebo for 10 to 14 days.

  4. Maujar says:

    Of the patients recruited, were randomized to receive treatment with intravenous magnesium sulfate and to receive saline placebo. In none of the subgroups did the magnesium sulfate group show a better outcome at 6 months.

  5. Fegul says:

    Pilot clinical trials using magnesium sulfate in patients with acute aneurysmal subarachnoid hemorrhage have reported trends toward improvement in clinical outcomes. In none of the subgroups did the magnesium sulfate group show a better outcome at 6 months.

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